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Which of the following substances can affect the ability to drive?

  1. Tranquilizers, marijuana, and sedatives

  2. Cough syrups and cold tablets containing codeine or antihistamines

  3. All of the above

  4. None of the above

The correct answer is: All of the above

All of the substances listed in the question can affect a person's ability to drive safely. Tranquilizers, marijuana, and sedatives can cause drowsiness, slow reaction times, and impair coordination. Cough syrups and cold tablets containing codeine or antihistamines can also cause drowsiness and impair cognitive function. Therefore, it is important to avoid driving when under the influence of these substances to ensure the safety of yourself and others on the road.